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A group of researchers led by Osaka University established a new pathological grading system to evaluate the therapeutic effect of neoadjuvant chemotherapy for metastatic lymph nodes removed in esophageal cancer surgery, demonstrating that the system predicts recurrence and prognosis in EC patients better than conventional systems.
Biomedical engineers at Duke University have engineered a method for simultaneously detecting the presence of multiple specific microRNAs in RNA extracted from tissue samples without the need for labeling or target amplification.
American researchers have published their new findings on gum disease in a research letter in the latest issue of the journal Gut titled, "Periodontal disease, tooth loss, and risk of oesophageal and gastric adenocarcinoma: a prospective study."
The incidence of esophageal adenocarcinoma has increased 8-fold over the past 50 years. This is one of the deadliest cancers, with a five-year survival rate of only 20 percent. However, the survival rate more than doubles if the cancer is identified early.
A unique nanoparticle to deliver a localized cancer treatment inhibits tumor growth in mice, according to a team of Penn State researchers.
Cancers arise when the genetic code of normal cells is altered, causing excessive growth. Researchers from the Cancer Science Institute of Singapore at the National University of Singapore have discovered a protein that drives the growth of cancers of the esophagus or liver by altering the genetic code in a novel way.
Black patients with esophageal cancer are at a higher risk of death compared to white patients. Although many reasons have been suggested for this, few have given physician actionable information.
The adoptive T-cell therapy ADP-A2M4, which is engineered to express a T-cell receptor (TCR) directed against the MAGE-A4 cancer antigen, achieved responses in patients with multiple solid tumor types, including synovial sarcoma, head and neck cancer and lung cancer, according to results from a Phase I clinical trial led by researchers at The University of Texas MD Anderson Cancer Center.
Results of the NRG Oncology clinical trial RTOG 1010 indicated that the addition of the monoclonal antibody trastuzumab to neoadjuvant trimodality treatment did not improve disease-free survival outcomes for patient with HER2 overexpressing local and locally advanced esophageal adenocarcinoma.
Aspirin is associated with a reduction in the risk of developing several cancers of the digestive tract, including some that are almost invariably fatal, such as pancreatic and liver cancers.